neurology · Review
Carotid Artery Stenting Is Now an Evidence-Based Adjunct to Intensive Medical Therapy for Stroke Prevention.
Meschia James F JF
Neurology · Sep 22, 2026 · PMID 42691470 · DOI 10.1212/WNL.0000000000218441
Abstract (English)
The CREST-2 trial demonstrated that carotid artery stenting combined with intensive medical management (IMM) significantly reduces stroke risk in patients with high-grade asymptomatic carotid stenosis compared with IMM alone. Careful patient selection and operator skill are critical factors for procedural success and can provide real-world validation of stenting as an important adjunct to IMM for stroke prevention. Continued advances in medical management and stenting are expected. It remains vital to engage in shared decision-making when considering moving forward with stenting of asymptomatic carotid stenosis.
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